A-level Biology Year 12 · AQA
AQA A-level Biology Year 12 revision
Every topic of the AQA A-level Biology (7402) specification (Year 12) in order, with notes and practice questions. Subtopics marked free have their notes and questions on this site.
Topic 1: Biological molecules
It builds on what you learned at GCSE in Organisation and Bioenergetics, and takes it further.
There are 7 parts: we start with monomers, polymers and carbohydrates, and finish with water and inorganic ions.
- 1.1Monomers, polymers and carbohydratesFree 35 questions
- 1.2Biochemical tests for carbohydrates, lipids and proteins (Benedict's, iodine, biuret, emulsion)39 questions
- 1.3Lipids28 questions
- 1.4Proteins and enzyme action67 questions
- 1.5Practical: investigating factors affecting the rate of enzyme-controlled reactions60 questions
- 1.6Nucleic acids and ATP28 questions
- 1.7Water and inorganic ions29 questions
Topic 2: Cells
It builds on what you learned at GCSE in Cell biology and Infection and response, and takes it further.
There are 14 parts: we start with cell structure, and finish with clonal selection, vaccination, herd immunity, monoclonal antibodies and autoimmune disease.
- 2.1Cell structureFree 71 questions
- 2.2Microscopy: magnification, resolution and light, TEM, SEM and laser scanning microscopes70 questions
- 2.3Cell fractionation and ultracentrifugation39 questions
- 2.4Prokaryotic cells and binary fissionFree 67 questions
- 2.5Viruses: structure, replication and HIV30 questions
- 2.6Practical: preparing temporary slides, using a light microscope and calibrating an eyepiece graticuleFree 61 questions
- 2.7Cell division and the cell cycle51 questions
- 2.8Practical: root tip squash, observing mitosis and calculating mitotic index69 questions
- 2.9Cell differentiation, stem cells, tissues, organs and organ systems73 questions
- 2.10Transport across cell membranes31 questions
- 2.11Practical: effect of temperature or solvent on cell membrane permeability (beetroot)53 questions
- 2.12Practical: dilution series and calibration curve to determine water potential of plant tissue21 questions
- 2.13Cell recognition and the immune system36 questions
- 2.14Clonal selection, vaccination, herd immunity, monoclonal antibodies and autoimmune disease20 questions
Topic 3: Organisms exchange substances with their environment
It builds on what you learned at GCSE in Organisation, and takes it further.
There are 8 parts: we start with surface area to volume ratio and gas exchange, and finish with mass transport in plants.
- 3.1Surface area to volume ratio and gas exchangeFree 33 questions
- 3.2Lung disease, risk factors and interpreting lung function data82 questions
- 3.3Practical: dissection of a gas exchange or mass transport system (fish gills, insect trachea, lungs, heart, plant stem)51 questions
- 3.4Digestion and absorption24 questions
- 3.5Mass transport in animals33 questions
- 3.6Blood, tissue fluid, lymph and blood clotting61 questions
- 3.7Cardiovascular disease: risk factors, correlation and causation35 questions
- 3.8Mass transport in plants31 questions
Topic 4: Genetic information, variation and relationships between organisms
It builds on what you learned at GCSE in Inheritance, variation and evolution and Ecology, and takes it further.
There are 13 parts: we start with DNA, genes and chromosomes, and finish with balancing human needs and conservation.
- 4.1DNA, genes and chromosomesFree 26 questions
- 4.2DNA and protein synthesis27 questions
- 4.3Genetic diversity: mutation and meiosis25 questions
- 4.4Genetic diversity, adaptation and biodiversity23 questions
- 4.5Antibiotics, antibiotic resistance and controlling the spread of disease31 questions
- 4.6Practical: aseptic technique and the effect of antimicrobial substances on microbial growth42 questions
- 4.7Species, binomial nomenclature and the taxonomic hierarchy31 questions
- 4.8Phylogeny, the three domains and five kingdoms, and molecular evidence for relationships36 questions
- 4.9Natural selection, evidence for evolution and speciation34 questions
- 4.10Investigating biodiversity: random sampling, transects, mark-release-recapture and Simpson's index67 questions
- 4.11Why biodiversity matters: ecological, economic, ethical and aesthetic reasonsFree 27 questions
- 4.12Human activities that reduce biodiversity: agriculture, deforestation and climate change22 questions
- 4.13Balancing human needs and conservation: evaluating data and management strategies67 questions
Topic S: Practical and maths skills
It builds on what you learned at GCSE in Working scientifically and maths skills, and takes it further.
There are 7 parts: we start with planning and designing investigations, and finish with drawing conclusions and evaluating methods, evidence and sources.
- S.1Planning and designing investigations: variables, controls, risk assessment and ethicsFree 35 questions
- S.2Apparatus and techniques: measurement, serial dilution, colorimetry, chromatography and vitamin C (DCPIP) titration26 questions
- S.3Processing and presenting data: tables, graphs, rates, gradients and percentage change67 questions
- S.4Mathematical skills: SI units, standard form, ratios, logarithms, surface area and volume, and magnification calculations49 questions
- S.5Statistical tests: mean, standard deviation, error bars, t-test, chi-squared and correlation (Spearman's rank)59 questions
- S.6Uncertainty, accuracy, precision, validity and reliability32 questions
- S.7Drawing conclusions and evaluating methods, evidence and sources36 questions